Grant Lythe, mathematical immunology, mathematical modelling



Stochastic modelling and mathematical immunology


QUANTI: Initial Training Network 2013-2017
IndoEuropean MathDS: mathematics for health and disease 2012-2016
INTI: International Network in Theoretical Immunology EU IRSES network 2009-2013
Immunology, Imaging and ModellingBBSRC MATSYB network 2008-2011
Robin Callard
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses Stephan Wilmes, Polly-Anne Jeffrey, Jonathan Martinez-Fabregas, Maximillian Hafer, Paul K Fyfe, Elizabeth Pohler, Silvia Gaggero, Martín López-García, Grant Lythe, Charles Taylor, Thomas Guerrier, David Launay, Suman Mitra, Jacob Piehler, Carmen Molina-París, Ignacio Moraga
eLife (2021)
Agent-Based Model of Heterogeneous T-Cell Activation in Vitro Shamik Majumdar, Carmen Molina-París, Dipankar Nandi and Grant Lythe Springer (2021)
supplementary
Stochastic dynamics of Francisella tularensis infection and replication Jonathan Carruthers, Tom laws, Joseph Gillard, Roman Lukaszewski, Martín López-García, Grant Lythe and Carmen Molina-París
PLoS Computational Biology (2020)
agent-based model and ABC codes
First passage events in biological systems with non-exponential inter-event times Mario Castro, Martín López-García, Grant Lythe and Carmen Molina-París
Scientific Reports 8 15054 (2018)
Some deterministic and stochastic models of naive T-cell homeostasis Grant Lythe and Carmen Molina-París
Immunological reviews 285 (2018)
The T Cells in an Ageing Virtual Mouse Mario Castro, Grant Lythe and Carmen Molina-París
Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology pp 127-14 (2017)
A new mechanism shapes the naive CD8+ T cell repertoire Pedro Goncalves, Marco Ferrarini, Carmen Molina-París, Grant Lythe, Florence Vasseur, Annik Lim, Bendita Rocha and Orly Azogui
Molecular Immunology 85 66 (2017)
Sampling from T cell receptor repertoires Marco Ferrarini, Carmen Molina-París and Grant Lythe.
Contributions in Mathematical and Computational Sciences
Continuous Effector CD8+ T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population H. Hamlet Chu, Shiao-Wei Chan, John Paul Gosling, Nicolas Blanchard, Alexandra Tsitsiklis, Grant Lythe, Nilabh Shastri, Carmen Molina-París, Ellen A. Robey
Immunity
How many TCR clonotypes does a body maintain? Grant Lythe, Robin E. Callard, Rollo L. Hoare and Carmen Molina-París
Journal of Theoretical Biology
Mathematics in modern immunology Mario Castro, Grant Lythe, Carmen Molina-París and Ruy M. Ribeiro. Interface focus
Modelling early events in Francisella tularensis pathogenesis Grant Lythe, Joseph Gillard, Thomas Laws and Carmen Molina-París
Frontiers in Cellular and Infection Microbiology
Accurate stationary densities with partitioned numerical methods for stochastic partial differential equations Kevin Burrage and Grant Lythe
Stochastic Partial Differential Equations: Analysis and Computations
A mathematical perspective on CD4+ T cell quorum-sensing Joseph Reynolds, InĂªs F. Amado, Antonio A. Freitas, Grant Lythe and Carmen Molina-París
Journal of Theoretical Biology